Letter | Published:

Increased Incidence of Avian Leukosis in Response to Excess Vitamin A

Naturevolume 214pages287288 (1967) | Download Citation



IT has been reported that a high plane of nutrition increases the incidence of avian leukosis resulting from either natural infection1 or from inoculation with strain RPL–12 virus2. In one experiment2 the birds were maintained on different planes of nutrition only from hatching until one month after inoculation with RPL–12 virus, and thereafter were fed on a low plane of nutrition. The higher incidence of leukosis in the birds subjected to nutritional excess only for a month following inoculation indicates an effect mediated at or before tumour genesis. In the above experiments, the different planes of nutrition involved different levels of many nutrients. In the experiments reported here, vitamin A by itself was observed to affect the incidence of avian leukosis.

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  1. University of British Columbia, Vancouver, Canada

    • B. E. MARCH
    •  & JACOB BIELY


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