Letter | Published:

Continuous Automatic Fluorometric Evaluation of Total Blood Histamine

Naturevolume 214pages279281 (1967) | Download Citation

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Abstract

AMONG the numerous methods of estimating blood histamine, the fluorometric method seems to be one of the most sensitive and specific1, but it is not very easy to carry out2. We have recently adapted and modified this method for use with the ‘Technicon’ auto-analyser. An extension of this method makes possible the continuous determination of blood histamine and is here used to investigate the activity of some histamine releasers.

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References

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    Shore, A. P., Burkhalter, A., and Cohn, V. H., J. Pharmacol., 127, 182 (1959).

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    Kremzner, L. T., and Pfeiffer, C. C., Biochem. Pharmacol., 15, 197 (1966).

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  1. Chaire de Physiologie II, Faculté de Médecine, Paris

    • FRANÇOIS RUFF
    • , ANATOLE SAINDELLE
    • , EUGÈNE DUTRIPON
    •  & JEAN-LOUIS PARROT

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https://doi.org/10.1038/214279b0

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