Letter | Published:

Purification of Human Angiotensin

Naturevolume 214pages278279 (1967) | Download Citation



INVESTIGATIONS of angiotensin have increased, especially since the description of the structures of bovine and horse angiotensin and the synthesis of chemically pure angiotensins1–3. Although knowledge of angiotensin has accumulated from animal and laboratory investigations, the exact role of angiotensin in the development of human hypertension is still obscure.

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    Arakawa, K., and Bumpus, M. F., J. Amer. Chem. Soc., 83, 728 (1961).

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    Schwarz, H., Bumpus, F. M., and Page, I. H., J. Amer. Chem. Soc., 79, 5697 (1957).

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    Rittel, W., Iselin, B., Kappeler, H., Riniker, B., and Schwyzer, R., Helv. Chim. Acta, 40, 614 (1957).

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    Lentz, K. E., Skeggs, jun., L. T., Woods, K. R., Kahn, J. R., and Shumway, N. P., J. Exp. Med., 104, 183 (1956).

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    Peart, W. S., Biochem. J., 62, 520 (1956).

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    Haas, E., Lamfrom, H., and Goldblatt, H., Arch. Biochem. Biophys., 48, 256 (1954).

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    Arakawa, K., Nakatani, M., and Nakamura, M., Nature, 207, 636 (1965).

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  1. Research Institute of Angiocardiology and Cardiovascular Clinic, Kyushu University School of Medicine, Fukuoka, Japan



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