Letter | Published:

Sub-units of Acid Phosphatase-1 in Drosophila melanogaster: Reversible Dissociation in vitro

Naturevolume 214pages274275 (1967) | Download Citation



THE genetic control of an acid phosphatase in the sibling species Drosophila melanogaster and D. simulans has been reported by one of us1. “Slow” and “fast” electrophoretic variants of this enzyme, called acid phosphatase-1 or Acph-1, are specified by codominant alleles, Acph-1A and Acph-1B, of a gene located very near the right end of chromosome 3 in each species. Zymograms of the heterozygotes (and interspecific hybrids) show three bands or zones of acid phosphataso activity: the “slow” and “fast” or Acph-1AA and Acph-1BB forms of the enzyme which are characteristic of the homozygous parents, and a third, more heavily staining zone which occupies a position between the parental enzymes.

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  1. Section of Genetics, Development and Physiology, Division of Biological Sciences, Cornell University, Ithaca, New York



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