Abstract
RECENTLY, metronidazole (‘Flagyl’) has been used in the treatment of alcoholism1 and it has been suggested that it might inhibit alcohol dehydrogenase2. We wish to present evidence to shed light on this suggestion.
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References
Taylor, J. A. T., Bull. Los Angeles Neurolog. Soc., 29, 158 (1964).
Metronidazole in Alcoholism. Preliminary Information for Clinical Investigators (second edition) (May and Baker Ltd., 1966).
von Wartburg, J. P., Papenberg, J., and Aebi, H., Canad. J. Biochem., 43, 889 (1965).
Kane, P. O., McFadzean, J. A., Squires, S., King, A. J., and Nicol, C. S., Brit. J. Vener. Dis., 37, 273 (1961).
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EDWARDS, J., PRICE, J. Metronidazole and Human Alcohol Dehydrogenase. Nature 214, 190–191 (1967). https://doi.org/10.1038/214190b0
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DOI: https://doi.org/10.1038/214190b0
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