Letter | Published:

Differential Sensitivity of Some Phases of the Mitotic Cycle to Temperature Effects in Two Types of Cell Populations in Day Old Rats

Naturevolume 214pages110111 (1967) | Download Citation



THE different sensitivity of some phases of the mitotic cycle to the effect of low temperatures has been demonstrated on cells of human amnion cultured in vitro1. It was of interest to compare these results with the evidence of an analogous investigation of cell populations in natural conditions from in vivo experiments. Animals used were day old rats which had no complex thermoregulatory mechanisms2,3. All investigations were made on two types of cell population of the wall of the duodenum: renewing (intestine epithelium) and expanding (smooth muscles) cells.

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    Sisken, J., Morasca, L., and Kibby, S., Exp. Cell Res., 39, 103 (1965).

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    Gulick, A., Ontogenesis of the Thermal Regulation in New-born Rats, Abstracts of the XV International Congress of Physiologists, 134 (1935).

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    Antoshkina, E., Physiol. J. (U.S.S.R.), 26, 2 (1939).

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    Stanners, C., and Till, J., Biochem. Biophys. Acta, 37, 406 (1960).

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    Zavarzin, A., in The Research of Cell Cycles and Metabolism of Nucleic Acids at Cell Differentiation, 37 (M-L, 1965).

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  1. Laboratory of Cell Morphology, Institute of Cytology, Academy of Sciences of the U.S.S.R., Leningrad

    •  & A. ZAVARZIN


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