Abstract
Khairallah and Page1 have tried our method2 for measuring angiotensin in blood and report almost complete loss of added angiotensin as well as the production of a new vasopressor substance during chemical extraction. Because these results differ from previous experience, the method has been reassessed to find out whether such differences are inherent in the technique, or are caused by their different application of the technique. Repetition of the previously reported control experiments2 has confirmed our original results.
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References
Khairallah, P. A., and Page, I. H., Nature, 206, 835 (1965).
Morris, R. E., and Robinson, P. R., Bull. Johns Hopkins Hosp., 114, 127 (1964).
Boucher, R., Biron, P., and Genest, J., Canad. J. Biochem., 39, 581 (1961).
Paladini, A. C., Braun-Menendez, E., Del Frade, I. S., and Massani, F. M., J. Lab. and Clin. Med., 53, 264 (1959).
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MORRIS, R., ROBINSON, P. Measurement of Angiotensin II in Blood. Nature 213, 936–937 (1967). https://doi.org/10.1038/213936a0
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DOI: https://doi.org/10.1038/213936a0
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