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Controlled Investigations in Baboons (Papio cynocephalus) on Transmission of SV-5 Virus by Contact

Abstract

THE intranasal infection of vervet monkeys (Cercopithecus aethiops) with SV-5 virus, which belongs to the parainfluenza 2 group1, has been reported to result in a disease pattern usually observed in naturally occurring parainfluenza virus infections of man2,3. It was suggested, therefore, that this experimental model was potentially useful for the evaluation of appropriate antiviral drugs and also for investigation of the pathology and pathogenesis of acute respiratory viral disease.

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References

  1. Andrewes, C., Viruses of Vertebrates, 130 (Baillière, Tindall and Cox, London, 1964).

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  2. Larin, N. M., Herbst-Laier, R. H., and Heath, R. B., Proc. Third Intern. Congr. Chemother., Stuttgart, 1963, 775 (Georg Thieme Verlag, Stuttgart, 1964).

  3. Heath, R. B., Islah, El F., Stark, J. E., Herbst-Laier, R. H., and Larin, N. M., Brit. J. Exp. Pathol., 47, 1, 93 (1966).

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LARIN, N., HERBST-LAIER, R., COPPING, M. et al. Controlled Investigations in Baboons (Papio cynocephalus) on Transmission of SV-5 Virus by Contact. Nature 213, 827–828 (1967). https://doi.org/10.1038/213827b0

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