Abstract
THERE has been considerable interest in myotonia, but current theories of its cause are based on evidence obtained in experiments where nerve and muscle responses could not be separated. Microphysiological investigation at a single neuromuscular junction can provide some information about pre- and post-synaptic factors and can also be used to study the common assertion1,2 that the disorder arises from “electrical instability” in the muscle membrane.
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HOFMANN, W., ROWE, G. Electrophysiological Study of Myotonia. Nature 212, 954 (1966). https://doi.org/10.1038/212954a0
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DOI: https://doi.org/10.1038/212954a0
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