Letter | Published:

Albumin Absorption by Renal Proximal Tubule Cells

Naturevolume 212pages546547 (1966) | Download Citation



IT is widely accepted that different types of foreign proteins are absorbed by renal proximal tubule cells when present in the glomerular filtrate. Very little is known, however, about the way in which proximal tubules handle serum proteins, although these may be present in the proximal tubule fluid under both normal1,2 and pathological conditions. The present experiments were carried out to determine whether homologous serum albumin can be absorbed by proximal tubule cells and, if so, to determine by means of autoradiography at the electron microscopical level which cellular components participate in the absorption.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Walker, A. M., Bott, P. A., Oliver, J., and MacDowell, M. C., Amer. J. Physiol., 134, 580 (1941).

  2. 2

    Dirks, J. H., Clapp, J. R., and Berliner, R. W., J. Clin. Invest., 43, 916 (1964).

  3. 3

    McFarlane, A. S., Nature, 182, 53 (1958).

  4. 4

    Smith, R. E., and Farquhar, M. G., Scientific Instruments News, 10, 13 (1965).

  5. 5

    de Duve, C., in Lysosomes, Ciba Found. Symp., edit. by de Reuck, A. V. S., and Cameron, M. P., 1 (Little, Brown and Company, Boston, 1963).

  6. 6

    Novikoff, A. B., in Lysosomes, Ciba Found. Symp., edit. by de Reuck, A. V. S., and Cameron, M. P., 36 (Little, Brown and Company, Boston, 1963).

  7. 7

    Maunsbach, A. B., J. Ultrastruct. Res., 16, 13 (1966).

Download references

Author information

Author notes


    Present address: Department of Anatomy, Karolinska Institutet, Stockholm, Sweden


  1. Department of Zoology, University of California, Los Angeles, California



  1. Search for ARVID B. MAUNSBACH in:

About this article

Publication history

Issue Date



Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.