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Binding of Noradrenaline to Smooth Muscle Cells in the Spleen

Abstract

NORADRENALINE infused close arterially into the cat spleen at a rate of 0.625 µg/min, equivalent to the physiological rate of release of this transmitter when stimulating the splenic nerves at 10 impulses/sec, is mainly bound to nerve endings within the spleen1,2.

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References

  1. Gillespie, J. S., and Kirpekar, S. M., J. Physiol., 178, 44 (1965).

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  2. Gillespie, J. S., and Kirpekar, S. M., J. Physiol., 179, 46 (1965).

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  3. Falck, B., Acta Physiol. Scand., 56 (Suppl.), 197 (1962).

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  4. Gillespie, J. S., and Kirpekar, S. M., J. Physiol., 176, 205 (1965).

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GILLESPIE, J., HAMILTON, D. Binding of Noradrenaline to Smooth Muscle Cells in the Spleen. Nature 212, 524–525 (1966). https://doi.org/10.1038/212524a0

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