Letter | Published:

Elevation of the Concentration of Plasma Oxalic Acid in Renal Failure

Naturevolume 212pages511512 (1966) | Download Citation



SEVERAL workers have identified crystals of calcium oxalate in the kidneys and myocardium in patients dying with renal failure1–6. Macaluso and Berg2 considered that the deposits are caused by local factors in the affected tissues, while others have suggested that they result from the retention of oxalic acid because of oliguria or to an increased endogenous production of oxalic acid or both4–6.

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    Laas, S., Zentbl. Allg. Path. Anat., 95, 157 (1965).

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    Macaluso, M. P., and Berg, N. O., Acta Path. Microbiol. Scand., 46, 197 (1959).

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    Bednar, B., Jirasek, A., Stejskal, J., and Chytil, M., Zentbl. Allg. Path. Anat., 102, 289 (1960).

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    Mayer, G. G., Markow, D., and Karp, F., Clin. Chem., 9, 334 (1963).

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    Williams, R. E., Smith, A. H., Young, G. A., Parsons, F. M., and Reed, G. W., Brit. J. Surg., 51, 544 (1964).

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  1. Medical Research Council, Mineral Metabolism Unit

    •  & A. HODGKINSON
  2. Renal Research Unit, The General Infirmary, Leeds

    • F. M. PARSONS


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