Letter | Published:

An Unusual Amino Sugar Derivative from the Cell Wall of Penicillium notatum

Naturevolume 212pages434435 (1966) | Download Citation



DURING the course of an investigation into the chemistry of the cell wall of Penicillium notatum an unusual amino sugar was detected in acid hydrolysates of the walls. It was present in only small amounts, but was easily visible by paper chromatography. The material was isolated from a 4 normal hydrochloric acid hydrolysate (carried out at 100° C for 24 h) and was purified by elution from Whatman 3 MM paper using solvent system B. It gave a positive reaction with the silver nitrate1, aniline phosphate2, ninhydrin and Elson–Morgan3 sprays, suggesting that the compound is probably a 2-deoxy, 2-amino sugar.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Trevelyan, W. E., Procter, D. P., and Harrison, J. S., Nature, 155, 444 (1950).

  2. 2

    Smith, I., Chromatographic and Electrophoretic Techniques, 1, 251 (Heinemann, London, 1960).

  3. 3

    Smith, I., Chromatographic and Electrophoretic Techniques, 1, 252 (Heinemann, London, 1960).

  4. 4

    Smith, E. J., Leatherwood, J. M., and Wheat, R. W., J. Bact., 84, 1008 (1962).

  5. 5

    Cifonelli, J. A., and Dorfman, A., J. Biol. Chem., 231, 11 (1958).

  6. 6

    Tipper, D. J., and Strominger, J. L., Biochem. Biophys. Res. Commun., 22, 48 (1966).

  7. 7

    Hestrin, S., J. Biol. Chem., 180, 249 (1949).

  8. 8

    Sharon, N., and Jeanloz, R. W., J. Biol. Chem., 235, 1 (1960).

Download references

Author information


  1. Department of Pathology, University of British Columbia, Vancouver



  1. Search for D. A. APPLEGARTH in:

About this article

Publication history

Issue Date



Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.