Letter | Published:

Pulmonary Tumours in Rats induced by Oral Hydrazine Sulphate

Naturevolume 212pages414415 (1966) | Download Citation

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Abstract

RATS provide good material for the study of pulmonary carcinogens since spontaneous pulmonary tumours are very rare. They have never been observed in colonies maintained by Orr and Bielschowsky1 or by Mori2, and when Wilson et al.3 killed about 1,500 rats and carried out histological examinations on all the organs suspected of neoplasia, they did not observe pulmonary tumours.

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References

  1. 1

    Orr, J. W., and Bielschowsky, F., Brit. J. Cancer, 1, 396 (1947).

  2. 2

    Mori, K., Gann, 53, 303 (1962).

  3. 3

    Wilson, R. H., DeEds, F., and Cox, A. J., jun., Cancer Res., 1, 595 (1941).

  4. 4

    Bianciflori, C., and Ribacchi, R., Nature, 194, 488 (1962).

  5. 5

    Bianciflori, C., Bucciarelli, E., Clayson, D. B., and Santilli, F. E., Brit. J. Cancer, 18, 543 (1964).

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Affiliations

  1. Division of Cancer Research, University of Perugia, P.O. Box 167

    • C. BIANCIFIORI
    • , F. E. GIORNELLI-SANTILLI
    • , U. MILIA
    •  & L. SEVERI

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https://doi.org/10.1038/212414b0

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