Letter | Published:

Number of Cytoplasmic Factors in Yeast Cells

Nature 212, 304 (1966) | Download Citation

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Abstract

IT is well known that the self-reproducing genetic factors (ρ), required for the development of mitochondria, are present in the cytoplasm of yeast cell. When the cells are allowed to grow in a medium containing acriflavine or related dyes, large numbers of mutant cells with deficient respiration are produced, which tend to dominate the entire cell population after several generations1.

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References

  1. 1

    Ephrussi, B., Nucleo-cytoplasmic Relations in Micro-organisms, 13 (The Clarendon Press, Oxford, 1953).

    • 2

      Sugimura, T., Okabe, K., and Rudney, H., Biochim. Biophys. Acta, 82, 350 (1964).

    • 3

      Ogur, M., John, R. S., and Nagai, S., Science, 125, 928 (1958).

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    Affiliations

    1. Biochemistry Division

      • TAKASHI SUGIMURA
      •  & KAZUKO OKABE

    2. Biophysics Division, National Cancer Center Research Institute, Tsukiji, Chuo-ku, Tokyo, Japan

      • AKIRA IMAMURA

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    https://doi.org/10.1038/212304a0

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