Letter | Published:

Adenosine Triphosphate Dependent Calcium Binding of Microsomes and Nerve Endings

Naturevolume 212pages291292 (1966) | Download Citation



NOWADAYS, it is fairly well established that calcium not only affects the excitability of the nerve cell membrane1 but that it is an important constituent of the membrane itself2. In this communication we contrast adenosine triphosphate (ATP) dependent calcium binding by the microsomal fraction of brain and liver cells and the nerve ending fraction of neurones with that by the sarcoplasmic reticulum of muscle cells and the mitochondrial fractions of brain and liver cells.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Shanes, A. M., Pharmacol. Rev., 10, 59 (1958).

  2. 2

    Tobias, J. M., J. Cell. Comp. Physiol., 52, 89 (1958).

  3. 3

    Whittaker, V. P., Biochem. J., 72, 694 (1959).

  4. 4

    Gray, E. G., and Whittaker, V. P., J. Anat., 96, 79 (1962).

  5. 5

    Vasington, F. D., and Murphy, J. V., J. Biol. Chem., 237, 2670 (1962).

  6. 6

    Rossi, C. S., and Lehninger, A. L., Biochem. Z., 338, 698 (1963).

  7. 7

    Hasselbach, W., and Makinose, M., Biochem. Z., 333, 518 (1961).

  8. 8

    Hasselbach, W., and Makinose, M., Biophys. Res. Commun., 7, 132 (1962).

  9. 9

    Schatzmann, H. J., Helv. Physiol. Pharmacol. Acta, 11, 346 (1953).

  10. 10

    Ebashi, S., and Lipmann, F., J. Cell Biol., 14, 389 (1962).

  11. 11

    Otsuka, M., Ohtsuki, I., and Ebashi, S. (unpublished observation).

Download references

Author information


  1. Department of Pharmacology, Faculty of Medicine, University of Osaka, Osaka, Japan

    • H. YOSHIDA
    • , K. KADOTA
    •  & H. FUJISAWA


  1. Search for H. YOSHIDA in:

  2. Search for K. KADOTA in:

  3. Search for H. FUJISAWA in:

About this article

Publication history

Issue Date



Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.