Letter | Published:

Use of Radioactive Isotopes in Studies on Phagocytosis in vitro

Naturevolume 212pages210211 (1966) | Download Citation



APART from its simplicity and certain other advantages, the microscopic method of studying phagocytosis by calculating the phagocytic index—that is the mean number of bacteria engulfed by one phagocyte—is time-consuming and its evaluation tends to be subjective. The faults of the classical phagocytic reaction can be avoided by using bacteria labelled with a radioactive isotope. Determination of the numbers of bacteria in the phagocytes can then be made with the help of a Geiger-Müller counter. The principle of the method for studying phagocytosis, however, remains unaltered.

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  1. 1

    Davis, B. D., in Methods in Medical Research, edit. by Lederberg, J., 3, 5 (1950).

  2. 2

    Kwiatkowska, J., and Morawiecki, A., Arch. Immunol. Therap. Exp., 11, 715 (1963).

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  1. Department of Microbiology, School of Medicine, Wroclaw



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