Abstract
HUMAN immunoglobulins are complex molecules which contain at least two types of polypeptide chains known as “heavy” and “light”1,2. The four classes of human immunoglobulins (IgG, IgM, IgA and IgD) differ in their heavy chains, (γ, μ, α and σ, respectively). Two types of light chains, χ and λ, are common to all3,4. In the case of IgG globulins, four subclasses of γ chains are now recognized5,6. This communication presents evidence for the existence of at least two antigenically distinguishable subgroups of α chains in IgA myeloma proteins.
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FEINSTEIN, D., FRANKLIN, E. Two Antigenically Distinguishable Subclasses of Human A Myeloma Proteins differing in their Heavy Chains. Nature 212, 1496–1498 (1966). https://doi.org/10.1038/2121496a0
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DOI: https://doi.org/10.1038/2121496a0
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