Letter | Published:

Adherence of Latex Particles to Platelets

Naturevolume 212pages7980 (1966) | Download Citation



WHEN platelets in citrated plasma are exposed to latex (polystyrene) particles, the particles adhere to the platelets1 and are phagocytosed by them2. In association with this process, the platelets undergo clumping. Both the phagocytosis and the aggregation depend on the presence of divalent cations, as they are inhibited by the sodium salt of ethylenediaminetetraacetic acid (EDTA). It seemed important, then, to determine whether the initial adherence between particles and platelets was also dependent on the presence of divalent cations.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Glynn, M. F., Movat, H. Z., Murphy, E. A., and Mustard, J. F., J. Lab. Clin. Med., 65, 179 (1965).

  2. 2

    Movat, H. Z., Weiser, W. J., Glynn, M. F., and Mustard, J. F., Cell Biol. (in the press).

  3. 3

    Roberts, J., and Quastel, J. H., Biochem. J., 89, 150 (1963).

  4. 4

    Hovig, T., Thromb. et Diath. Hemorrh., 9, 264 (1963).

  5. 5

    Hughes, J., and Lapiere, Ch. M., Thromb. et Diath. Hemorrh., 11, 327 (1964).

Download references

Author information

Author notes

  1. M. F. GLYNN: From the National Heart Institute, National Institutes of Health, Bethesda, Maryland.


  1. Blood and Vascular Disease Research Unit, Departments of Medicine and Pathology, University of Toronto

    • M. F. GLYNN
    • , R. HERREN
    •  & J. F. MUSTARD
  2. Department of Veterans Affairs, Sunnybrook Hospital, Toronto

    • M. F. GLYNN
    • , R. HERREN
    •  & J. F. MUSTARD


  1. Search for M. F. GLYNN in:

  2. Search for R. HERREN in:

  3. Search for J. F. MUSTARD in:

About this article

Publication history

Issue Date



Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.