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Antibodies to Synthetic Corticotrophin

Abstract

ADRENOCORTICOTROPHIC hormone (ACTH) is a polypeptide of particular interest as its structure is known, it has been synthesized, and the molecule has both biological and antigenic activities. In earlier publications1,2 it was shown that antibodies to highly purified pig ACTH induced in the guinea-pig form a soluble complex with ACTH labelled with iodine-131, and that this binding is reversible.

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References

  1. Felber, J. P., Experientia, 19, 227 (1963).

    Article  CAS  Google Scholar 

  2. Felber, J. P., Radioakt. Isotop., 6, 368 (1965). Ashcroft, S. H. J., Villanueva, A., and Felber, J. P., Chimia, 18, 283 (1964).

    Google Scholar 

  3. Schwyzer, R., and Sieber, P., Nature, 199, 178 (1963).

    Article  ADS  Google Scholar 

  4. Kappeler, H., and Schwyzer, R., Helv. Chim. Acta, 44, 1136 (1961).

    Article  CAS  Google Scholar 

  5. Lebovitz, H. E., and Engel, F. L., Metabolism, 13, 1230 (1964).

    Article  CAS  Google Scholar 

  6. Lebovitz, H. E., and Engel, F. L., Endocrinology, 73, 573 (1963).

    Article  CAS  Google Scholar 

  7. Wieland, O., in Methoden der Enzymatischen Analyse, 211, edit. by Bergmeyer, H. U. (1962).

    Google Scholar 

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FELBER, J., ASHCROFT, S., VILLANUEVA, A. et al. Antibodies to Synthetic Corticotrophin. Nature 211, 654–655 (1966). https://doi.org/10.1038/211654a0

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