Abstract
FORMALDEHYDE reacts with ethylenic double bonds in the presence of an acid catalyst to give 1 : 3 glycols and 1 : 3 dioxanes (the Prins reaction)1. This reaction is well documented2,3 and the following sequence is generally accepted: (a) Formation of electrophilic species: (b) Reaction with double bond:
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References
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Adams, C. W. M. (personal communication).
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JONES, D., GRESHAM, G. Reaction of Formaldehyde with Unsaturated Fatty Acids during Histological Fixation. Nature 210, 1386–1388 (1966). https://doi.org/10.1038/2101386b0
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DOI: https://doi.org/10.1038/2101386b0
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