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Chemosterilization of Aedes aegypti (L.) by Pupal Treatment

Abstract

THE concept of insect control through the liberation of sterile males1 proved successful in the eradication of the screw-worm fly (Cochliomyia hominivorax) from the south-eastern United States2. Following this success, in which sterility was induced by γ-irradiation, interest was taken in the possibility of inducing sexual sterility by chemical means3. Screening of chemicals yielded several substances with a prospective sterilizing capacity4,5, notably alkylating agents incorporating the aziridine moiety. In general they are less injurious to insects than radiation6,7, and treatment of insects with chemicals is in certain respects more convenient than the procedures of irradiation.

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WHITE, G. Chemosterilization of Aedes aegypti (L.) by Pupal Treatment. Nature 210, 1372–1373 (1966). https://doi.org/10.1038/2101372b0

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