Abstract
IRON-52 has been used in this hospital since 19571. As it is a positron emitter, coincidence counting techniques are used to investigate the distribution of erythropoietic tissue in patients with a variety of haematological disorders. In addition, its short half-life (8.2 h) has made it possible to investigate the effect of cytotoxic agents and ionizing radiation on marrow function by serial measurements at various intervals. It has also proved of value in the study of the kinetics of iron in animals. In some of the disorders studied, the iron-binding capacity of the serum may be low, and iron-52 of the highest specific activity is therefore desirable.
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References
Francois, P. E., and Szur, L., Nature, 182, 1165 (1958).
Yano, Y., and Anger, H. O., Intern. J. App. Rad. Isotopes, 16, 153 (1965).
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SILVESTER, D., SUGDEN, J. Production of Carrier-free Iron-52 for Medical Use. Nature 210, 1282–1283 (1966). https://doi.org/10.1038/2101282a0
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DOI: https://doi.org/10.1038/2101282a0
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