This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Large-scale in silico mutagenesis experiments reveal optimization of genetic code and codon usage for protein mutational robustness
BMC Biology Open Access 20 October 2020
-
The influence of different types of translational inaccuracies on the genetic code structure
BMC Bioinformatics Open Access 06 March 2019
-
The optimality of the standard genetic code assessed by an eight-objective evolutionary algorithm
BMC Evolutionary Biology Open Access 13 December 2018
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Epstein, C. J., Nature, 203, 1350 (1964).
Anfinsen, C. B., Brookhaven Symp. Biol., 15, 194 (1962).
Kauzmann, W., Adv. Prot. Chem., 14, 1 (1959).
Kendrew, J. C., Brookhaven Symp. Biol., 15, 216 (1962).
Perutz, M. F., J. Mol. Biol., 13, 646 (1965).
Perutz, M. F., Kendrew, J. C., and Watson, H. C., J. Mol. Biol., 13, 669 (1965).
Fisher, H. F., Proc. U.S. Nat. Acad. Sci., 51, 1285 (1964).
Blake, C. C. F., Koenig, D. F., Mair, G. A., North, A. C. T., Phillips, D. C., and Sarma, V. R., Nature, 206, 757 (1965).
Nirenberg, M. W., Jones, O. W., Leder, P., Clark, B. F. C., Sly, W. S., and Pestka, S., Cold Spring Harb. Symp. Quant. Biol., 28, 549 (1963).
Brimacombe, R., Trupen, J., Nirenberg, M., Leder, P., Bernfield, M., and Jaoumi, R., Proc. U.S. Nat. Acad. Sci., 54, 954 (1965).
Woese, C. R., Proc. U.S. Nat. Acad. Sci., 54, 71 (1965).
Volkenstein, M. V., Nature, 207, 294 (1965).
Pelc, S. R., Nature, 207, 597 (1965).
Konigsberg, W., and Hill, R. J., J. Biol. Chem., 237, 3157 (1962).
Beale, D., and Lehmann, H., Nature, 207, 259 (1965).
Ingram, V. M., Nature, 187, 704 (1961).
Schroeder, W. A., Shelton, J. R., Shelton, J. B., Cormick, J., and Jones, R. T., Biochem., 2, 992 (1963).
Freese, E., and Yoshida, A., in Evolving Genes and Proteins, edit. by Bryson, V., and Vogel, H. J., 377 (New York, Academic Press, 1965).
Margoliash, E., and Smith, E., in Evolving Genes and Proteins, edit. by Bryson, V., and Vogel, H. J., 221 (New York, Academic Press, 1965).
Stretton, A. O. W., and Brenner, S., J. Mol. Biol., 12, 456 (1965).
Sonneborn, R. M., in Evolving Genes and Proteins, edit. by Bryson, V., and Vogel, H. J., 377 (New York, Academic Press, 1965).
Woese, C. R., Proc. U.S. Nat. Acad. Sci., 54, 1546 (1965).
Versteeg, D. H. G., and Vliegenthart, J. F. G., Experientia, 21, 615 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
EPSTEIN, C. Role of the Amino-Acid ‘Code’ and of Selection for Conformation in the Evolution of Proteins. Nature 210, 25–28 (1966). https://doi.org/10.1038/210025a0
Issue Date:
DOI: https://doi.org/10.1038/210025a0
This article is cited by
-
The structure of the genetic code as an optimal graph clustering problem
Journal of Mathematical Biology (2022)
-
Large-scale in silico mutagenesis experiments reveal optimization of genetic code and codon usage for protein mutational robustness
BMC Biology (2020)
-
The influence of different types of translational inaccuracies on the genetic code structure
BMC Bioinformatics (2019)
-
How to ‘find’ an error minimized genetic code: neutral emergence as an alternative to direct Darwinian selection for evolutionary optimization
Natural Computing (2019)
-
The Quality of Genetic Code Models in Terms of Their Robustness Against Point Mutations
Bulletin of Mathematical Biology (2019)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.