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References
- 1
Epstein, C. J., Nature, 203, 1350 (1964).
- 2
Anfinsen, C. B., Brookhaven Symp. Biol., 15, 194 (1962).
- 3
Kauzmann, W., Adv. Prot. Chem., 14, 1 (1959).
- 4
Kendrew, J. C., Brookhaven Symp. Biol., 15, 216 (1962).
- 5
Perutz, M. F., J. Mol. Biol., 13, 646 (1965).
- 6
Perutz, M. F., Kendrew, J. C., and Watson, H. C., J. Mol. Biol., 13, 669 (1965).
- 7
Fisher, H. F., Proc. U.S. Nat. Acad. Sci., 51, 1285 (1964).
- 8
Blake, C. C. F., Koenig, D. F., Mair, G. A., North, A. C. T., Phillips, D. C., and Sarma, V. R., Nature, 206, 757 (1965).
- 9
Nirenberg, M. W., Jones, O. W., Leder, P., Clark, B. F. C., Sly, W. S., and Pestka, S., Cold Spring Harb. Symp. Quant. Biol., 28, 549 (1963).
- 10
Brimacombe, R., Trupen, J., Nirenberg, M., Leder, P., Bernfield, M., and Jaoumi, R., Proc. U.S. Nat. Acad. Sci., 54, 954 (1965).
- 11
Woese, C. R., Proc. U.S. Nat. Acad. Sci., 54, 71 (1965).
- 12
Volkenstein, M. V., Nature, 207, 294 (1965).
- 13
Pelc, S. R., Nature, 207, 597 (1965).
- 14
Konigsberg, W., and Hill, R. J., J. Biol. Chem., 237, 3157 (1962).
- 15
Beale, D., and Lehmann, H., Nature, 207, 259 (1965).
- 16
Ingram, V. M., Nature, 187, 704 (1961).
- 17
Schroeder, W. A., Shelton, J. R., Shelton, J. B., Cormick, J., and Jones, R. T., Biochem., 2, 992 (1963).
- 18
Freese, E., and Yoshida, A., in Evolving Genes and Proteins, edit. by Bryson, V., and Vogel, H. J., 377 (New York, Academic Press, 1965).
- 19
Margoliash, E., and Smith, E., in Evolving Genes and Proteins, edit. by Bryson, V., and Vogel, H. J., 221 (New York, Academic Press, 1965).
- 20
Stretton, A. O. W., and Brenner, S., J. Mol. Biol., 12, 456 (1965).
- 21
Sonneborn, R. M., in Evolving Genes and Proteins, edit. by Bryson, V., and Vogel, H. J., 377 (New York, Academic Press, 1965).
- 22
Woese, C. R., Proc. U.S. Nat. Acad. Sci., 54, 1546 (1965).
- 23
Versteeg, D. H. G., and Vliegenthart, J. F. G., Experientia, 21, 615 (1965).
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EPSTEIN, C. Role of the Amino-Acid ‘Code’ and of Selection for Conformation in the Evolution of Proteins. Nature 210, 25–28 (1966). https://doi.org/10.1038/210025a0
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