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Electrophoretic Behaviour of H and L Chains of Human Serum and Colostrum Gamma-globulin

Nature volume 209, pages 926–928 (1966)Cite this article

Abstract

DISSOCIATION of gamma-globulin molecules by reduction in urea with such thiol reagents as mercapto-ethanol and thioglycolate1,2, or in neutral aqueous solution3, or by S-sulphonation4,5, allows the identification of two types of polypeptide chain, called H, (A) and L (B), which may be separated by gel filtration.

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Authors and Affiliations

  1. Department of Immunology, Institute of Microbiology, Czechoslovak Academy of Sciences, Prague

    J. REJNEK, J. KOSTKA & O. KOTÝNEK

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  1. J. REJNEK
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  2. J. KOSTKA
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  3. O. KOTÝNEK
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REJNEK, J., KOSTKA, J. & KOTÝNEK, O. Electrophoretic Behaviour of H and L Chains of Human Serum and Colostrum Gamma-globulin. Nature 209, 926–928 (1966). https://doi.org/10.1038/209926b0

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