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Induction of Chromosome Injuries in Mouse Bone Marrow under the Distant Effect of Ionizing Radiation

Abstract

DESTRUCTIVE processes are known to be absent from shielded regions of the haemopoietic system but present in irradiated regions1,2. Yet it has been shown that shortly after irradiation the concentration of deoxyribonucleotides and nucleosides decreases. This is followed by a decrease in DNA in the cells of both irradiated and shielded regions of the bone marrow3,4. DNA synthesis has also been found to be inhibited not only in irradiated but also, to a somewhat lesser degree, in shielded tumours5,6.

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BARAKINA, N., YANUSHEVSKAYA, M. Induction of Chromosome Injuries in Mouse Bone Marrow under the Distant Effect of Ionizing Radiation. Nature 209, 823–824 (1966). https://doi.org/10.1038/209823a0

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