Abstract
KUFFLER et al.1–3 have shown that in the frog there are two very distinct types of skeletal muscle fibres; one, the more common, is capable of generating spikes and giving twitches; while the other is not. Further differences that fibres of the spike type are innervated by fast nerve fibres and give only a transient contraction to maintained depolarization. On the other hand, when similarly stimulated, the non-spike type of muscle fibre produces a prolonged contraction. These ‘slow’ muscle fibres are multiply innervated by slow nerve fibres.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Kuffler, S. W., and Gerard, R. W., J. Neurophysiol., 10, 383 (1947).
Kuffler, S. W., and Vaughan-Williams, E. M., J. Physiol., 121, 289 (1953).
Kuffler, S. W., and Vaughan-Williams, E. M., J. Physiol., 121, 318 (1953).
Buller, A. J., Eccles, J. C., and Eccles, R. M., J. Physiol., 150, 417 (1960).
Feng, T. P., Wu, W. Y., and Yang, F. Y., Sci. Sinica., 14, 1717 (1965).
Miledi, R., J. Physiol., 154, 190 (1960).
Peachey, L. D., and Huxley, A. F., J. Cell. Biol., 13, 177 (1962).
Page, S. G., J. Cell. Biol., 26, 477 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MILEDI, R., ORKAND, P. Effect of a ‘Fast’ Nerve on ‘Slow’ Muscle Fibres in the Frog. Nature 209, 717–718 (1966). https://doi.org/10.1038/209717a0
Issue Date:
DOI: https://doi.org/10.1038/209717a0
This article is cited by
-
Effect of denervation on pigeon slow skeletal muscle
Zeitschrift f�r Zellforschung und Mikroskopische Anatomie (1972)
-
Early stage of re-innervation of frog slow muscle fibres
Pfl�gers Archiv European Journal of Physiology (1972)
-
Zur Morphologie der Bauelemente von Muskelspindeln bei Mensch und Ratte
Zeitschrift f�r Zellforschung und Mikroskopische Anatomie (1969)
-
Neurotrophic Control of Contracture in Slow Muscle Fibres
Nature (1968)
-
Motor End-plates in Fast and Slow Muscles of the Chick after Cross-union of their Nerves
Nature (1967)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.