Abstract
BLOOD platelets suspended in plasma readily exhibit aggregation when small amounts of adenosine diphosphate are added1. Aggregation can also be produced by the addition of 5-hydroxytryptamine2,3 since this has been shown to release ADP from platelets4, Born et al. have shown that adenosine, its analogues or related substances, when added prior to an aggregating dose of ADP or 5-HT will inhibit the aggregation and may prevent it altogether1,5,6.
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References
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MICHAL, F., THORP, R. Enhanced Adenosine Inhibition of Platelet Aggregation in the Presence of Cardiac Glycosides. Nature 209, 208–209 (1966). https://doi.org/10.1038/209208a0
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DOI: https://doi.org/10.1038/209208a0
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