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Stability of a Radioactive Drug—Tetrasodium 2-Methyl-1,4-naphthaquinol Diphosphate labelled with Tritium

Abstract

THIS communication describes the decomposition by self-irradiation of the radioactive drug tetrasodium 2-methyl-1,4-naphthaquinol diphosphate labelled in the 5,6 and/or 7 positions with tritium. The possible radio-therapeutic use of this labelled compound in the treatment of certain types of cancer is at present under investigation by Prof. J. S. Mitchell and colleagues at the University of Cambridge1,2.

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References

  1. Mitchell, J. S., Strahlentherapie, 127, 497 (1965).

    CAS  PubMed  Google Scholar 

  2. Mitchell, J. S., Clin. Radiol., 16, 305 (1965).

    Article  CAS  Google Scholar 

  3. Bayly, R. J., and Weigel, H., Nature, 188, 384 (1960).

    Article  ADS  CAS  Google Scholar 

  4. Evans, E. A., and Stanford, F. G., Nature, 197, 551 (1963).

    Article  ADS  CAS  Google Scholar 

  5. Radiochemical Center, Amersham Review Series No. 3 (April 1965).

  6. Evans, E. A., see p. 169 of this issue of Nature

  7. Andrews, K. J. M., Bultitude, F., Evans, E. A., Gronow, M., Lambert, R. W., and Marrian, D. H., J. Chem. Soc., 3440 (1962).

  8. Evans, E. A., and Stanford, F. G., Nature, 199, 762 (1963).

    Article  ADS  CAS  Google Scholar 

  9. Apelgot, S., Ekert, B., and Tisne, M. R., Proc. Conf. on Methods of Preparing and Storing Marked Molecules, Brussels (November 1963). European Atomic Energy Community, Euratom, EUR 1625 e, 939 (May 1964).

  10. Apelgot, S., and Ekert, B., paper presented at the colloquium on “Chemical Stability and Biological Use of Tritiated Pyrimidine Nucleosides”. Euratom, Mol (Belgium), March 16–18, 1965.

  11. Apelgot, S., and Ekert, B., J. Chim. Phys., 62, 845 (1965).

    Article  CAS  Google Scholar 

  12. Apelgot, S., and Frilley, M., J. Chim. Phys., 62, 838 (1965).

    Article  CAS  Google Scholar 

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EVANS, E. Stability of a Radioactive Drug—Tetrasodium 2-Methyl-1,4-naphthaquinol Diphosphate labelled with Tritium. Nature 209, 196–197 (1966). https://doi.org/10.1038/209196a0

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