Abstract
IN a previous communication1 we reported a striking example of enzymatic dedifferentiation as observed in a chemically induced squamous cell carcinoma subjected to serial transplantation by various routes. The present communication describes the variations in activity of six hydrolytic enzymes and five dehydrogenases in benzpyrene-induced cervico-vaginal carcinoma, solid transplantable squamous cell carcinoma and in four ascites lines. These results complete our investigations of the changes occurring in the enzymatic equipment of squamous cells during the course of neoplastic degeneration.
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References
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THIERY, M., WILLIGHAGEN, R. Dynamic Study of the Phenomenon of Enzymatic Dedifferentiation. Nature 209, 1243–1244 (1966). https://doi.org/10.1038/2091243a0
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DOI: https://doi.org/10.1038/2091243a0
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