Abstract
PREVIOUSLY, a high nucleo-cytoplasmic concentration gradient of sodium was found in rat liver and other tissues1,2. Since the concentration of potassium also was higher in the nucleus than in the cytoplasm, about 500 µequiv./g dry weight of anions should exist in the nucleus if the assumption is correct that nucleic acids and basic proteins approximately neutralize each other. This communication presents data which demonstrate a high concentration of chloride in the nucleus of the rat-liver cell.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Itoh, S., and Schwartz, I. L., Amer. J. Physiol., 188, 490 (1957).
Langendorf, H., Siebert, G., Lorenz, I., Hannover, R., and Beyer, R., Biochem. Z., 335, 273 (1961).
Siebert, G., Biochem. Taschenbuch, edit. by Rauen, second ed., 2, 541 (Springer-Verlag, 1964).
Beyermann, K., and Cretius, K., Clin. Chim. Acta, 6, 113 (1961).
Tölg, G., Z. Anal. Chem., 194, 20 (1963).
Siebert, G., and Humphrey, G. B., Adv. Enzymol., 27, 239 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LANGENDORF, H., SIEBERT, G., KESSELRING, K. et al. High Nucleo-cytoplasmic Concentration Gradient of Chloride in Rat Liver. Nature 209, 1130–1131 (1966). https://doi.org/10.1038/2091130b0
Issue Date:
DOI: https://doi.org/10.1038/2091130b0
This article is cited by
-
Features of in vitro puffing and RNA synthesis in polytene chromosomes of Chironomus
Chromosoma (1980)
-
Isolation and properties of nonhistone chromosomal proteins from pea chromatin
Molecular and Cellular Biochemistry (1973)
-
Ionenhaushalt im Zellkern
Die Naturwissenschaften (1970)
-
Kinetics of NAD reduction in the nucleus and the cytoplasm
Histochemie (1968)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.