Abstract
Cohen and Porter1 have demonstrated that the light (L) chains of human IgG globulins can be separated into ten subtractions by starch-gel electrophoresis. They also showed that the L chains of guinea-pig anti-ovalbumin and anti-(bovine serum albumin) separated into ten subfractions, but the intensity of the staining of the bands differed from each other and from those of L chains obtained from IgG globulins. The work presented here is concerned with the distribution of 125I-labelled L chains of human antibody among the ten subtractions.
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References
Cohen, S., and Porter, R. R., Biochem. J., 90, 278 (1964).
Fleischman, J. B., Pain, R. H., and Porter, R. R., Arch. Biochem. Biophys. Suppl. No. 1, 174 (1962).
Hughes-Jones, N. C., Gardner, B., and Telford, R., Immunology, 7, 72 (1964).
Cohn, E. J., and Edsall, J. T., Proteins, Amino-acids and Peptides, 85 (Reinhold Publishing Corporation, 1943).
Hughes-Jones, N. C., Gardner, B., and Telford, R., Biochem. J., 88, 435 (1963).
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HUGHES-JONES, N. Iodine-125-labelled L Chains of Human Blood Group Antibodies. Nature 207, 989–990 (1965). https://doi.org/10.1038/207989a0
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DOI: https://doi.org/10.1038/207989a0
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