Letter | Published:

Simultaneous Chromatographic Separation and Infra-red Sample Preparation of Indole Acids

Naturevolume 207pages977978 (1965) | Download Citation

Subjects

Abstract

IN attempting to identify trace amounts of metabolites from biological fluids, the use of one of the most powerful tools of organic chemical analysis, infra-red spectroscopy, presents technical difficulties. The two major ones are: (a) a sample preparation technique for the characteristically polar compounds, and (b) sufficient purity to allow a resolvable spectrum.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Mandell, A. J., Sabbot, I. M., Mandell, M. P., and Kollar, E. J., Arch. Gen. Psychiat., 10, 229 (1964).

  2. 2

    Morgan, P. J., The Analyst, 86, 631 (1961).

  3. 3

    Krivis, A. F., Bronson, G. E., Struck, W. A., and Johnson, J. L., Microchem. J., 8, 277 (1961).

  4. 4

    Sloan, H. J., Anal. Chem., 35, 1556 (1963).

  5. 5

    Thomas, P., and Dwyer, J. J., Chromatog., 13, 366 (1963).

  6. 6

    Millipore Filter Corp. App. Man., ADM–70 (Bedford, Mass., 1963).

  7. 7

    Millich, F., and Becker, E. I., J. Org. Chem., 23, 1096 (1958).

Download references

Author information

Affiliations

  1. Department of Psychiatry, University of California Medical Center, Los Angeles, 24

    • ARNOLD J. MANDELL

Authors

  1. Search for ARNOLD J. MANDELL in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/207977a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.