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Strange Male Block to Pregnancy: its Absence in Inbred Mouse Strains

Naturevolume 207page878 (1965) | Download Citation



A SERIES of papers by Bruce and colleagues1–4 has described a pre-implantation block to pregnancy in non-inbred laboratory mice which is evoked by the presence of strange males of the same strain or of a different strain (‘alien’ males). This effect is olfactory-mediated. The phenomenon has also been reported in another species, non-inbred prairie deermice (Peromyscus maniculatus bairdii)5.

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  1. 1

    Bruce, H. M., J. Reprod. Fertil., 1, 96 (1960).

  2. 2

    Bruce, H. M., J. Reprod. Fertil., 1, 311 (1960).

  3. 3

    Bruce, H. M., and Parrott, D. M. V., Science, 131, 1526 (1960).

  4. 4

    Parkes, A. S., and Bruce, H. M., Science, 134, 1049 (1961).

  5. 5

    Bronson, F. H., and Eleftheriou, B. E., Gen. Comp. Endocrinol., 8, 515 (1963).

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  1. The Jackson Laboratory, Bar Harbor, Maine

    • H. M. MARSDEN
    •  & F. H. BRONSON


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