Letter | Published:

Structure and Role of Cytoplasmic Ribonucleic Acid in Malignancy

Naturevolume 207pages772773 (1965) | Download Citation

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Abstract

X-RAY diffraction investigations1–4 have indicated that RNA of normal biological material exists as an oriented helical structure with the sugar-phosphate chains forming its circumference and the hydrogen-bound bases forming its central core. Despite the irregularity in the sequence of its bases5, RNA derives a certain degree of regularity from repetition of the C3—O—P—O—C5 internucleotide linkage and from the spatial configuration of the sugar–phosphate ‘backbones’.

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Affiliations

  1. Department of Obstetrics and Gynecology, Sabbatsbergs Hospital, Karolinska Institutet, Stockholm

    • M. SHERIF

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https://doi.org/10.1038/207772a0

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