Abstract
X-RAY diffraction investigations1–4 have indicated that RNA of normal biological material exists as an oriented helical structure with the sugar-phosphate chains forming its circumference and the hydrogen-bound bases forming its central core. Despite the irregularity in the sequence of its bases5, RNA derives a certain degree of regularity from repetition of the C3—O—P—O—C5 internucleotide linkage and from the spatial configuration of the sugar–phosphate ‘backbones’.
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SHERIF, M. Structure and Role of Cytoplasmic Ribonucleic Acid in Malignancy. Nature 207, 772–773 (1965). https://doi.org/10.1038/207772a0
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DOI: https://doi.org/10.1038/207772a0
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