Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Changes of Histone Composition in the Developing Chick Embryo

Nature volume 207, pages 638–640 (1965)Cite this article

Abstract

THE possible role of histones as gene suppressors has been discussed by many authors1–5. If histones do have such a function, one might expect to find some qualitative or quantitative changes in the histone pattern during the course of development, reflecting steps in the processes of differentiation. However, up to now no conclusive evidence of this has been produced. Small changes have been demonstrated in the electrophoretic pattern of total nuclear histone from embryonic chick liver during development6.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Stedman, E., and Stedman, E., Nature, 166, 780 (1950).

    Article  ADS  CAS  Google Scholar 

  2. Leisle, I., Nature, 189, 260 (1961).

    Article  ADS  Google Scholar 

  3. Bloch, D. P., J. Histochem. Cytochem., 10, 137 (1962).

    Article  CAS  Google Scholar 

  4. Allfrey, V. G., Littau, V. C., and Mirsky, A. E., Proc. U.S. Nat. Acad. Sci., 49, 414 (1963).

    Article  ADS  CAS  Google Scholar 

  5. Moore, B. C., Proc. U.S. Nat. Acad. Sci., 50, 1018 (1963).

    Article  ADS  CAS  Google Scholar 

  6. Lindsay, D. T., Science, 144, 420 (1964).

    Article  CAS  Google Scholar 

  7. Agrell, I. P. S., and Christensson, E. G., Nature, 191, 284 (1961).

    Article  ADS  CAS  Google Scholar 

  8. Johns, E. W., Phillips, D. M. P., Simson, P., and Butler, J. A. V., Biochem. J., 77, 631 (1960).

    Article  CAS  Google Scholar 

  9. Agrell, I. P. S., Pathol. Biol., 9, 775 (1961).

    CAS  PubMed  Google Scholar 

  10. Neelin, J. M., and Butler, G. C., J. Biochem. Physiol., 39, 488 (1961).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Zoophysiological Institute, University of Lund, Sweden

    I. P. S. AGRELL & E. G. CHRISTENSSON

Authors
  1. I. P. S. AGRELL
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. G. CHRISTENSSON
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

AGRELL, I., CHRISTENSSON, E. Changes of Histone Composition in the Developing Chick Embryo. Nature 207, 638–640 (1965). https://doi.org/10.1038/207638a0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/207638a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing