Abstract
ANGIOTENSIN, the most potent pressor substance known, strongly suspected as a cause of renal hypertension, is an octapeptide formed from angiotensinogen by the action of renin. It has long been thought that only primate renins are capable of acting on human angiotensinogen as reviewed by Braun-Menéndez et al.1.
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Braun-Menéndez, E., Fasciolo, J. C., Leloir, L. F., Muñoz, J. M., and Taquini, A. C., Renal Hypertension, 113 (Springfield: Thomas, 1946).
Boucher, B., Veyrat, R., de Champlain, J., and Genest, J., Canad. Med. Assoc. J., 90, 194 (1964).
Skeggs, jun., E. T., Marsh, W. H., Kahn, J. R., and Shumway, N. P., J. Exp. Med., 100, 363 (1954).
Peart, W. S., Biochem. J., 59, 300 (1955).
Haas, E., Lamfrom, H., and Goldblatt, H., Arch. Biochem. Biophys., 48, 256 (1953).
Cohn, E. J., Strong, L. E., Hughes, jun., W. L., Mulford, D. J., Ashworth, J. N., and Taylor, H. L., J. Amer. Chem. Soc., 68, 459 (1946).
Arakawa, K., and Bumpus, M. F., J. Amer. Chem. Soc., 83, 728 (1961).
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ARAKAWA, K., NAKATANI, M. & NAKAMURA, M. Species Specificity in Reaction between Renin and Angiotensinogen. Nature 207, 636 (1965). https://doi.org/10.1038/207636a0
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DOI: https://doi.org/10.1038/207636a0
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