Relation of Cell Size to the Effect of X-rays on Poliovirus Production by Monkey-kidney Cells

Abstract

IN several systems of animal cells in tissue culture, irradiation with either X- or gamme-rays progressively reduces the ability to produce virus (that is, the ‘capacity’) until it is between 1 and 10 per cent of the capacity of non-irradiated control cultures. The remaining capacity is less radiosensitive, so that a graph depicting residual capacity of the test population as a function of radiation dose tends to level off1–3.

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LEVINE, S., OLSON, W. Relation of Cell Size to the Effect of X-rays on Poliovirus Production by Monkey-kidney Cells. Nature 207, 1411–1412 (1965). https://doi.org/10.1038/2071411a0

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