Appearance of Rat Slow Alpha-two Globulin after Irradiation


SLOW alpha-two globulin1 (SA2G), although not demonstrable by the usual method in the sera of healthy, non-pregnant, adult rats, appears in rat sera under a large number of conditions involving growth, regeneration, necrosis, inflammation, infection or the administration of bacterial lipopolysaccharide2,3. Consequently, it was considered of interest to determine whether or not SA2G could be demonstrated in the sera of rats subjected to irradiation alone or to irradiation followed by the administration of bacterial lipopolysaccharides.

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    Beaton, G. H., Selby, A. E., and Wright, A. M., J. Biol. Chem., 236, 2001 (1961).

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    Heim, W. G., and Lane, P. H., Nature, 203, 1077 (1964).

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    Boffa, G. A., Nadal, C., Zajdela, F., and Fine, J. M., Nature, 203, 1182 (1964).

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    Heim, W. G., Nature, 193, 491 (1962).

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    Smithies, O., Biochem. J., 71, 585 (1959).

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HEIM, W. Appearance of Rat Slow Alpha-two Globulin after Irradiation. Nature 207, 1403–1404 (1965).

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