Actomyosin and Myosin of Vascular Smooth Muscle


VARIOUS procedures have been used for extracting contractile protein from vascular smooth muscle1–3. In the course of preparing extracts from the cow carotid artery using a medium of 0.6 M KCl, the actomyosin content was estimated by measuring the ATP-sensitivity and viscosity number (Zη). In this report it will be shown that the extract from cow carotid artery consists of actomyosin and an actin-combining component, probably myosin, firmly associated with one another. It is believed that this firm association is a manifestation of unusual solubility properties of vascular smooth muscle myosin.

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MALLIN, M. Actomyosin and Myosin of Vascular Smooth Muscle. Nature 207, 1297–1298 (1965).

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