Serological Relationship between Adenovirus Haemagglutinins of Group 2


HETEROLOGOUS haemagglutination-inhibition (HI) antibody responses have recently been reported1 to occur in volunteers inoculated with adenovirus type 26 or type 27. A significantly increased frequency of type 13 responses was observed among men inoculated with type 26 as well as high frequencies of reciprocal responses between types 26 and 27. These findings were interpreted as indicating the existence of antigenic relationships among these types. Heterologous responses to 17 other types also occurred; however, these were less frequent and were distributed in an apparently random fashion, so that additional antigenic relationships between individual serotypes could not be identified.

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WIGAND, R., KASEL, J., ALLING, D. et al. Serological Relationship between Adenovirus Haemagglutinins of Group 2. Nature 207, 1207–1208 (1965).

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