Letter | Published:

Genetic and Non-genetic Factors in Chromatographic Behaviour of Poliovirus

Naturevolume 207pages10051006 (1965) | Download Citation



SOME variants of poliovirus (E+) do not adsorb on DEAE-cellulose provided neutral 0.01–0.02 M phosphate buffer is used as a diluent; under identical conditions some other variants (E−) are almost completely detained on the ion-exchanger and can be eluted only with solutions of increased ionic strength1,2. The E character of polio-virus may be considered as a genetic property which has no complete correlation with any other marker investigated so far3–6.

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  1. 1

    Hodes, H. L., Zepp, H. D., and Ainbender, E. A., Virology, 11, 306 (1960).

  2. 2

    Delsal, J.-L., Lépine, P., and Sautter, V., C.R. Acad. Sci. (Paris), 251, 290 (1960).

  3. 3

    Agol, V. I., Maslova, S. V., Chumakova, M. Ya., and Avgustinovich, G. I., Acta virologica (Prague), 6, 253 (1962).

  4. 4

    Agol, V. I., Maslova, S. V., and Chumakova, M. Ya., Biokhimia, 27, 1071 (1962).

  5. 5

    Maslova, S. V., and Agol, V. I. (in preparation).

  6. 6

    Boeyé, A., Virology, 21, 587 (1963).

  7. 7

    Pohjanpelto, P., Virology, 15, 205 (1961).

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  1. Institute of Poliomyelitis and Viral Encephalitides, Academy of Medical Sciences, Moscow, U.S.S.R.

    • S. V. MASLOVA
    •  & V. I. AGOL


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