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Heterologous and Homologous Skin-sensitizing Activity of Mouse 7S γ1- and 7S γ2-Globulins

Abstract

RECENT studies in the mouse have demonstrated two classes of 7S γ-globulins, the 7S γ1- and 7S γ2-globulins1. These two classes differ in electrophoretic mobility, antigenically, and in genetically determined isoantigens. Both classes possess antibody activity. Experiments to determine whether these two immunoglobulin classes possess skin-sensitizing activity were carried out in both heterologous (guinea-pig skin) and homologous (mouse skin) systems.

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References

  1. Fahey, J. L., Wunderlich, J., and Mishell, R., J. Exp. Med., 120, 223 (1964).

    Article  CAS  Google Scholar 

  2. Ovary, Z., Progress in Allergy, 5 (S. Karger, New York, 1958).

    Google Scholar 

  3. Ovary, Z., Barth, W. F., and Fahey, J. L., J. Immunol. (in the press).

  4. Fahey, J. L., and Wirtz, E. (in preparation).

  5. Ovary, Z., Benacerraf, B., and Bloch, K., J. Exp. Med., 117, 951 (1963).

    Article  CAS  Google Scholar 

  6. Ovary, Z., Fudenberg, H., and Kunkel, H. G., J. Exp. Med., 112, 1953 (1960).

    Article  Google Scholar 

  7. Ovary, Z., Bloch, K., and Benacerraf, B., Proc. Soc. Exp. Biol. and Med., 116, 840 (1964).

    Article  CAS  Google Scholar 

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BARTH, W., FAHEY, J. Heterologous and Homologous Skin-sensitizing Activity of Mouse 7S γ1- and 7S γ2-Globulins. Nature 206, 730–731 (1965). https://doi.org/10.1038/206730a0

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