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Total Optical Resolution of Free α-Amino-acids by the Inoculation Method

Abstract

SEVERAL investigations of the optical resolution of organic compounds by mechanical sorting1,2 and by preferential crystallization3–11 have been reported. This type of simple procedure of optical resolution would be the most advantageous method if we could obtain an optically pure isomer. However, in the reported resolution of DL-amino-acids, most of the methods were impractical or resulted in a partial resolution with the exception of the optical resolution of DL-glutamic acid9 and the copper salt of DL-aspartic acid11.

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HARADA, K. Total Optical Resolution of Free α-Amino-acids by the Inoculation Method. Nature 206, 1354–1355 (1965). https://doi.org/10.1038/2061354a0

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