Photolysis of L-Histidine


IT is well known that ultra-violet irradiation of proteins can cause changes of physiological importance but, despite the increasing number of publications on aspects of this problem, little is known of the primary processes which must precede or accompany the destruction of the macromolecule. Our interest is in the mechanism of the photolytic degradation of some of the simple aminoacids as an aid to a better understanding of the primary photolytic processes. This communication gives the results of a detailed, but qualitative, chemical investigation of the products of photolysis of L-histidine as a first step in this broader study.

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JOHNS, R., JASKEWYCZ, T. Photolysis of L-Histidine. Nature 206, 1149 (1965).

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