Hyperglycaemic Effect of Vasotocin in Toads


PREPARATIONS of neurohypophyseal hormones may increase blood glucose concentration in mammals, but the interpretation of the earlier reports was complicated by the possibility that the preparations were impure1. Mirsky2, however, has shown that pure preparations of neurohypophyseal hormones increase the blood glucose concentration of dogs by about 10 per cent and at the same time decrease the free fatty acid concentration.

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    Mirsky, I. A., Endocrinology, 73, 613 (1963).

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    Heller, H., in Comparative Endocrinology, edit. by von Euler U. S., and Heller, H., 1 (1963).

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    Hunter, N. W., and Johnson, C. E., J. Cell. Comp. Physiol., 55, 275 (1960).

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BENTLEY, P. Hyperglycaemic Effect of Vasotocin in Toads. Nature 206, 1053–1054 (1965) doi:10.1038/2061053a0

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