Potentiating Effect of Oxytocin on Contraction of Glycerine-extracted Psoas Muscle Fibre induced by Adenosine Triphosphate

Abstract

CLINICALLY it is a well-known phenomenon that whereas infusion of oxytocin increases the myometrial contractility, no such effect is noted on the skeletal muscle system. This is true even when as much as 3,000–4,000 mU of oxytocin is infused per min. It may be that this difference is the result of selective permeability properties of the membranes.

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References

  1. 1

    Szent-Györgyi, A., Chemistry of Muscular Contraction, second ed., 144 (Academic Press Inc., New York, 1951).

  2. 2

    Kumar, D., and Adams, P. R. (unpublished results).

  3. 3

    Kumar, D., Goodno, J. A., and Barnes, A. C., Amer. J. Obst. and Gynec., 84, 1111 (1962).

  4. 4

    Kumar, D., and Wagatsuma, T. (unpublished results).

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KUMAR, D., WAGATSUMA, T. & BARNES, A. Potentiating Effect of Oxytocin on Contraction of Glycerine-extracted Psoas Muscle Fibre induced by Adenosine Triphosphate. Nature 206, 1050 (1965) doi:10.1038/2061050a0

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