Letter | Published:

New Cellulose Derivatives for the Isolation of Biologically Active Molecules

Nature volume 204, pages 896897 (28 November 1964) | Download Citation



THE search for the relationship between structure and function of antibodies has gone through different phases. Much information has been accumulated concerning the interactions of antibody with antigens, particularly with respect to haptens of related and different structures. These data have given rise to a multitude of speculations concerning the chemical and physical structure of antibodies and the mechanism of antibody reactions. At present, major questions awaiting answers are: (1) Does antibody to a particular antigen have a unique primary structure ? (2) Do all antibodies have the same primary structure but they are folded differently ? (3) Are the antibody combining sites for a particular antigen the same, but are other parts of the antibody molecule modified for other functions ? (4) What is the composition and structure of the active site ?

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    , Brit. Med. Bull., 19, 183 (1963).

  2. 2.

    , and , Naturwiss., 42, 212 (1955).

  3. 3.

    , , , and , Immunochemistry (in the press).

  4. 4.

    , and , J. Amer. Chem. Soc., 85, 487 (1963).

Download references

Author information


  1. Space Science Division, Jet Propulsion Laboratory, California Institute of Technology, Pasadena.

    • H. H. WEETALL
    •  & N. WELIKY


  1. Search for H. H. WEETALL in:

  2. Search for N. WELIKY in:

About this article

Publication history




Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.